Clinical research
Every LYV compound is backed by peer-reviewed clinical data. These pages break down the key studies in plain language -- what they found, what it means, and what they don't prove.
Tirzepatide
SURMOUNT-1 Trial
Tirzepatide produced 22.5% average body weight loss over 72 weeks in people with obesity -- the largest weight reduction ever recorded in a Phase 3 trial of this size.
SURMOUNT-5 Trial
In the first head-to-head comparison, tirzepatide produced 47% more weight loss than semaglutide (Ozempic/Wegovy) over 72 weeks.
Tirzepatide vs Semaglutide: The 47% Difference
Across all available trial data, tirzepatide consistently produces approximately 47% more weight loss than semaglutide, driven by its dual GIP/GLP-1 mechanism.
Topical Hair Therapy
TH07 Hair Regrowth Trial
A combination topical formula (minoxidil + finasteride + latanoprost + ketoconazole) produced results 4x better than minoxidil alone in a Phase 2 trial.
Kaufman Finasteride 5-Year Study
90% of men on finasteride maintained or regrew hair over 5 years, while 100% of the placebo group continued losing hair.
Piraccini Topical Finasteride Phase III
Topical finasteride reduced scalp DHT comparably to oral finasteride while maintaining significantly lower systemic blood levels of the drug.
NAD+
NADPark Study
NAD+ supplementation significantly increased brain NAD+ metabolites and was well-tolerated in a clinical study examining neurological biomarkers.
Lancet NAD+ Blood Level Study
Direct NAD+ supplementation increased blood NAD+ levels 2.6-3.1x within weeks, far exceeding typical results from oral precursors like NMN or NR.
Sermorelin
Corpas Sermorelin Study
Sermorelin restored IGF-1 levels to youthful ranges within 14 days of treatment in healthy older adults.
Khorram Sermorelin RCT
5 months of sermorelin produced measurable improvements in body composition, including a 5% decrease in body fat measured by DEXA scan.
Glutathione
Richie Glutathione RCT
Six months of glutathione supplementation increased body GSH stores by 30-35%, with sustained elevation throughout the treatment period.
Sinha Glutathione Immunity Study
Glutathione supplementation increased natural killer (NK) cell cytotoxic activity by over 400% within two weeks.
Sildenafil + Tadalafil Gummy
Cui Sildenafil-Tadalafil Combination Study
Low-dose combination of sildenafil and tadalafil outperformed full-dose monotherapy of either drug in 180 men with ED, with no increase in side effects.
Eardley Sildenafil Onset Study
Sildenafil produced an 82% response rate, with clinical onset occurring as early as 12 minutes after dosing.
See which compounds match your goals
Take a 2-minute quiz. Get matched to a personalized protocol.